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glossary:dermatophytoses [2012/10/16 14:40] (current)
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|+||Dermatophytoses are fungal [[infection]]s of keratin in the skin and nails (nail [[infection]] is called tinea unguium—see Nail Disorders: Onychomycosis). Symptoms and signs vary by site of infection. Diagnosis is by clinical appearance and by examination of [[skin]] scraping on potassium hydroxide wet mount. Treatment varies by site but always involves topical or oral antifungal drugs. |
|+||Dermatophytes are molds that require keratin for nutrition and must live on stratum corneum, hair, or nails to survive. All human infections are caused by Epidermophyton , Microsporum , and Trichophyton spp. These differ from candidiasis in that they are rarely if ever invasive. Transmission is person-to-person, animal-to-person, and rarely, soil-to-person. The organism may persist indefinitely. Most people do not develop clinical infection; those who do may have impaired T-cell responses from an alteration in local defenses (eg from [[trauma]] with vascular compromise) or from primary (hereditary) or secondary (eg, diabetes, HIV) immunosuppression.|