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glossary:imipenem [2008/04/28 03:56]
Pat O'Connor
glossary:imipenem [2012/10/16 14:40] (current)
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 +(1) (Science: chemical) 6-(1-hydroxyethyl)-3-((2-((iminomethyl)amino)ethyl)thio)-7- oxo-1-azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid. Semisynthetic thienamycin that has a wide spectrum of antibacterial activity against [[gram-negative bacteria]] and [[gram-positive bacteria]] aerobic and anaerobic organisms]] (bacteria), including many multiresistant strains. It is stable to beta-lactamases. Clinical studies have demonstrated high efficacy in the treatment of infections of various body systems. Its effectiveness is enhanced when it is administered in combination with cilastatin, a renal dipeptidase inhibitor. ​
 +Pharmacological action: thienamycins. ​
 +Chemical name: 1-Azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid, 6-(1-hydroxyethyl)-3-((2-((iminomethyl)amino)ethyl)thio)-7-oxo-,​ (5R-(5alpha,​6alpha(R*)
 +(2) An [[antibiotic]] drug used to treat severe or very resistant [[infection]]. It belongs to the family of drugs called carbapenems.
 +See also:
 +[[http://​​phpBB2/​viewforum.php?​f=34|Antibiotic Glossary]]
 +[[http://​​|Antibiotics]] (blog)
glossary/imipenem.txt ยท Last modified: 2012/10/16 14:40 (external edit)